Notify people that OXYCONTIN may trigger orthostatic hypotension and syncope. Instruct sufferers how to acknowledge indicators of minimal blood pressure level and the way to reduce the chance of serious outcomes should hypotension manifest (e.
Request your doctor or pharmacist if you should have naloxone available to deal with opioid overdose. Teach Your loved ones or domestic customers about the indications of an opioid overdose and the way to deal with it.
This drug passes into breast milk and might have unwanted consequences with a nursing toddler. Notify the medical doctor at once When your toddler develops uncommon sleepiness, issues feeding, or difficulty breathing. Talk to your health practitioner just before breastfeeding.
Oxycodone hydrochloride tablets usually are not suggested for use in Gals for the duration of or instantly just before labor. Occasionally, opioid analgesics may well prolong labor by way of actions which briefly lessen the strength, length and frequency of uterine contractions.
Oxycodone hydrochloride tablets ought to be applied with Intense warning in people with substantial Long-term obstructive pulmonary disease or cor pulmonale, and in clients having considerably diminished respiratory reserve, hypoxia, hypercapnia, or pre-present respiratory despair.
Bear in mind this medication is prescribed for the reason that your medical professional has judged which the advantage for you is bigger than the risk of Uncomfortable side effects. Lots of people working with this medication would not have significant Unintended effects.
This doc does not contain all probable Unwanted side effects and Many others may perhaps come about. Check out with your medical doctor For extra information about Unintended effects.
Tell individuals and caregivers not to raise opioid dosage without 1st consulting a clinician. Suggest clients to seek health care focus whenever they knowledge indicators of hyperalgesia, which include worsening agony, amplified sensitivity to pain, or new discomfort [see WARNINGS AND PRECAUTIONS and ADVERSE REACTIONS].
Dispose of read more expired, unwanted, or unused OXYCONTIN by instantly flushing down the rest room, if a drug choose-again choice isn't readily available. Visit For added info on disposal of unused medicines.
If an individual has overdosed and it has severe signs or symptoms check here which include passing out or difficulty respiration, provide them with naloxone if available, then get in touch with 911. If the person is awake and has no indicators, connect get more info with a poison Manage Middle immediately.
Oxycodone hydrochloride was genotoxic within an in vitro mouse lymphoma assay during the presence of metabolic activation. There was no evidence of genotoxic prospective in an in vitro bacterial reverse mutation assay (Salmonella typhimurium and more info Escherichia coli) or within an assay for chromosomal aberrations (in vivo mouse bone marrow micronucleus assay).
OXYCONTIN® exposes patients as well as other customers on the pitfalls of opioid habit, abuse, and misuse, which can result in overdose and death.
There are actually scarce put up-marketing and advertising reports of scenarios of intestinal obstruction, and exacerbation of diverticulitis, a few of that have needed healthcare intervention to get rid of the tablet. Patients with underlying GI Diseases including esophageal most read more cancers or colon most cancers with a small gastrointestinal lumen are at larger danger of producing these complications.
Simply because respiratory despair could be greater than usually anticipated, minimize the dosage of OXYCONTIN and/or even the muscle mass relaxant as required.